Journal: Infection and Drug Resistance
Article Title:
Synergistic Effects from Combination of Cryptotanshinone and Fosfomycin Against Fosfomycin-Susceptible and Fosfomycin-Resistant Staphylococcus aureus
doi: 10.2147/idr.s255296
Figure Lengend Snippet: Figure 1 Early addition of cryptotanshinone potentiates the fosfomycin activity against FSSA and FRSA strains. Time-kill curves of S. aureus ATCC 25,923 and #122 strains in presence of cryptotanshinone, and fosfomycin alone or in combination with cryptotanshinone for 24 h. FOS, fosfomycin, CPT, cryptotanshinone.
Article Snippet: Table 1 Fosfomycin MICs and FSSA and FRSA Strains Description Pathogen Strain Reference/Source Description Fosfomycin MIC (μg/mL) S. aureus ATCC25923 American Type Culture Collection Fosfomycin-susceptible reference strain 2 #25 Lishui central hospital, zhejiang province Clinical isolate with a G790A base substitution of MurA, and C299T base substitution of GlpT and G1044T base substitution of UhpT 128 #28 Lishui central hospital, zhejiang province Clinical isolate with a G790A base substitution of MurA, and C299T base substitution of GlpT and G1044T base substitution of UhpT 64 #47 Lishui central hospital, zhejiang province Clinical isolate with a G790A base substitution of MurA, and C299T base substitution of GlpT and G1044T base substitution of UhpT 64 #87 Lishui central hospital, zhejiang province Clinical isolate with a G790A base substitution of MurA, and C299T base substitution of GlpT and G1044T base substitution of UhpT 64 #99 Lishui central hospital, zhejiang province Clinical isolate with a G790A base substitution of MurA, and C299T base substitution of GlpT and G1044T base substitution of UhpT 64 #122 Lishui central hospital, zhejiang province Clinical isolate with a G248 base deletion of GlpT 2048 #133 Lishui central hospital, zhejiang province Clinical isolate with a G248 base deletion of GlpT 2048 Infection and Drug Resistance 2020:13 submit your manuscript | www.dovepress.com DovePress 2839 In fe ct io n an d D ru g R es is ta nc e do w nl oa de d fr om h ttp s: //w w w .d ov ep re ss .c om / b y 19 3.
Techniques: Activity Assay